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Microscopy Cell Segmentation via Convolutional LSTM Networks

2018-05-29Code Available0· sign in to hype

Assaf Arbelle, Tammy Riklin Raviv

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Abstract

Live cell microscopy sequences exhibit complex spatial structures and complicated temporal behaviour, making their analysis a challenging task. Considering cell segmentation problem, which plays a significant role in the analysis, the spatial properties of the data can be captured using Convolutional Neural Networks (CNNs). Recent approaches show promising segmentation results using convolutional encoder-decoders such as the U-Net. Nevertheless, these methods are limited by their inability to incorporate temporal information, that can facilitate segmentation of individual touching cells or of cells that are partially visible. In order to exploit cell dynamics we propose a novel segmentation architecture which integrates Convolutional Long Short Term Memory (C-LSTM) with the U-Net. The network's unique architecture allows it to capture multi-scale, compact, spatio-temporal encoding in the C-LSTMs memory units. The method was evaluated on the Cell Tracking Challenge and achieved state-of-the-art results (1st on Fluo-N2DH-SIM+ and 2nd on DIC-C2DL-HeLa datasets) The code is freely available at: https://github.com/arbellea/LSTM-UNet.git

Tasks

Benchmark Results

DatasetModelMetricClaimedVerifiedStatus
DIC-C2DH-HeLaEncLSTMSEG (~Mean IoU)0.79Unverified
DIC-C2DH-HeLaDecLSTMSEG (~Mean IoU)0.51Unverified
Fluo-N2DH-GOWT1EncLSTMSEG (~Mean IoU)0.85Unverified
Fluo-N2DH-GOWT1DecLSTMSEG (~Mean IoU)0.85Unverified
Fluo-N2DH-SIM+EncLSTMSEG (~Mean IoU)0.81Unverified
Fluo-N2DH-SIM+DecLSTMSEG (~Mean IoU)0.8Unverified
Fluo-N2DL-HeLaDecLSTMSEG (~Mean IoU)0.84Unverified
Fluo-N2DL-HeLaEncLSTMSEG (~Mean IoU)0.81Unverified
PhC-C2DH-U373EncLSTMSEG (~Mean IoU)0.84Unverified

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