SOTAVerified

Single-step retrosynthesis

Papers

Showing 110 of 34 papers

TitleStatusHype
RETRO SYNFLOW: Discrete Flow Matching for Accurate and Diverse Single-Step Retrosynthesis0
Accelerating the inference of string generation-based chemical reaction models for industrial applications0
RetroGFN: Diverse and Feasible Retrosynthesis using GFlowNetsCode2
UAlign: Pushing the Limit of Template-free Retrosynthesis Prediction with Unsupervised SMILES AlignmentCode1
Node-Aligned Graph-to-Graph (NAG2G): Elevating Template-Free Deep Learning Approaches in Single-Step RetrosynthesisCode1
RetroBridge: Modeling Retrosynthesis with Markov BridgesCode1
Models Matter: The Impact of Single-Step Retrosynthesis on Synthesis Planning0
G-MATT: Single-step Retrosynthesis Prediction using Molecular Grammar Tree Transformer0
O-GNN: Incorporating Ring Priors into Molecular ModelingCode1
Mind the Retrosynthesis Gap: Bridging the divide between Single-step and Multi-step Retrosynthesis Prediction0
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Benchmark Results

#ModelMetricClaimedVerifiedStatus
1NAG2G (reaction class as prior)Top-1 accuracy67.2Unverified
2UAlign (reaction class as prior)Top-1 accuracy66.4Unverified
3MARS (reaction class as prior)Top-1 accuracy66.2Unverified
4RetroComposer (reaction class as prior)Top-1 accuracy65.9Unverified
5SemiRetro (reaction class as prior)Top-1 accuracy65.8Unverified
6O-GNN (reaction class as prior)Top-1 accuracy65.7Unverified
7Dual-TF (reaction class as prior)Top-1 accuracy65.7Unverified
8GraphRetro (reaction class as prior)Top-1 accuracy63.9Unverified
9LocalRetro (reaction class as prior)Top-1 accuracy63.9Unverified
10MEGAN (reaction class as prior)Top-1 accuracy60.7Unverified