SOTAVerified

Protein Design

Formally, given the design requirements of users, models are required to generate protein amino acid sequences that align with those requirements.

Papers

Recently AddedMost HypedMost ActiveNeeds VerificationMost Verified

Showing 126–150 of 175 papers

TitleStatusHype
Reinforcement Learning for Sequence Design Leveraging Protein Language Models—0
Rigidity strengthening is a vital mechanism for protein-ligand binding—0
RNACG: A Universal RNA Sequence Conditional Generation model based on Flow-Matching—0
Sparks: Multi-Agent Artificial Intelligence Model Discovers Protein Design Principles—0
Steering Protein Family Design through Profile Bayesian Flow—0
SurfPro: Functional Protein Design Based on Continuous Surface—0
TERMinator: A Neural Framework for Structure-Based Protein Design using Tertiary Repeating Motifs—0
The Dance of Atoms-De Novo Protein Design with Diffusion Model—0
Controllable Protein Design with Language Models—0
Towards deep learning sequence-structure co-generation for protein design—0
Toward the Explainability of Protein Language Models for Sequence Design—0
Training Free Guided Flow Matching with Optimal Control—0
Fast uncovering of protein sequence diversity from structure—0
UniIF: Unified Molecule Inverse Folding—0
Using GANs for De Novo Protein Design Targeting Microglial IL-3Rα to Inhibit Alzheimer's Progression—0
Validation of an LLM-based Multi-Agent Framework for Protein Engineering in Dry Lab and Wet Lab—0
Void distributions reveal structural link between jammed packings and protein cores—0
Plug-and-Play Controllable Generation for Discrete Masked Models—0
Prediction of amino acid side chain conformation using a deep neural network—0
Pre-training of Graph Neural Network for Modeling Effects of Mutations on Protein-Protein Binding Affinity—0
Prot42: a Novel Family of Protein Language Models for Target-aware Protein Binder Generation—0
ProtDAT: A Unified Framework for Protein Sequence Design from Any Protein Text Description—0
ProteinBench: A Holistic Evaluation of Protein Foundation Models—0
Protein design by multiobjective optimization: evolutionary and non-evolutionary approaches—0
Protein Design with Dynamic Protein Vocabulary—0
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All datasetsCATH 4.2CATH 4.3

Benchmark Results

#ModelMetricClaimedVerifiedStatus
1GraphTransPerplexity6.63—Unverified
2StructGNNPerplexity6.4—Unverified
3AlphaDesignPerplexity6.3—Unverified
4GCAPerplexity6.05—Unverified
5GVPPerplexity5.36—Unverified
6ProteinMPNNPerplexity4.61—Unverified
7PiFoldPerplexity4.55—Unverified
8Knowledge-DesignPerplexity3.46—Unverified
#ModelMetricClaimedVerifiedStatus
1ESM-IFPerplexity6.44—Unverified
2GVP-largePerplexity6.17—Unverified