| Enhancing the efficiency of protein language models with minimal wet-lab data through few-shot learning | Feb 3, 2024 | Few-Shot LearningLearning-To-Rank | —Unverified | 0 |
| Fast and Accurate Antibody Sequence Design via Structure Retrieval | Feb 11, 2025 | Graph Neural NetworkProtein Design | —Unverified | 0 |
| Fast fixed-backbone protein sequence and rotamer design | Sep 29, 2021 | Graph AttentionImitation Learning | —Unverified | 0 |
| Folding and Stabilization of Native-Sequence-Reversed Proteins | Jun 16, 2016 | Protein DesignProtein Folding | —Unverified | 0 |
| From thermodynamics to protein design: Diffusion models for biomolecule generation towards autonomous protein engineering | Jan 5, 2025 | DenoisingDrug Discovery | —Unverified | 0 |
| Annotation-guided Protein Design with Multi-Level Domain Alignment | Apr 18, 2024 | Protein AnnotationProtein Design | —Unverified | 0 |
| Generative AI for Controllable Protein Sequence Design: A Survey | Feb 16, 2024 | Drug DiscoveryProtein Design | —Unverified | 0 |
| Generative artificial intelligence for de novo protein design | Oct 15, 2023 | Protein Design | —Unverified | 0 |
| Generative modeling for protein structures | Dec 1, 2018 | Protein Design | —Unverified | 0 |
| Geometric deep learning assists protein engineering. Opportunities and Challenges | Jun 19, 2025 | Deep LearningProtein Design | —Unverified | 0 |
| Gradient-Informed Quality Diversity for the Illumination of Discrete Spaces | Jun 8, 2023 | DiversityDrug Discovery | —Unverified | 0 |
| Ideal gas behavior of rotamerically defined conformers in native globular proteins | Apr 30, 2015 | Drug DesignProtein Design | —Unverified | 0 |
| Implicitly Guided Design with PropEn: Match your Data to Follow the Gradient | May 28, 2024 | DecoderProtein Design | —Unverified | 0 |
| Improving Protein Sequence Design through Designability Preference Optimization | May 30, 2025 | Protein Design | —Unverified | 0 |
| Iterative Importance Fine-tuning of Diffusion Models | Feb 6, 2025 | Protein Design | —Unverified | 0 |
| Lattice protein design using Bayesian learning | Mar 14, 2020 | Protein Design | —Unverified | 0 |
| Learning immune receptor representations with protein language models | Feb 6, 2024 | DiversityDrug Discovery | —Unverified | 0 |
| Leveraging Deep Generative Model For Computational Protein Design And Optimization | Aug 30, 2024 | Protein DesignProtein Structure Prediction | —Unverified | 0 |
| CCPL: Cross-modal Contrastive Protein Learning | Mar 19, 2023 | Language ModelingLanguage Modelling | —Unverified | 0 |
| ProteinWeaver: A Divide-and-Assembly Approach for Protein Backbone Design | Nov 8, 2024 | Protein Design | —Unverified | 0 |
| ProteinZero: Self-Improving Protein Generation via Online Reinforcement Learning | Jun 9, 2025 | DiversityGPU | —Unverified | 0 |
| ProtFlow: Fast Protein Sequence Design via Flow Matching on Compressed Protein Language Model Embeddings | Apr 15, 2025 | Language ModelingLanguage Modelling | —Unverified | 0 |
| ProT-GFDM: A Generative Fractional Diffusion Model for Protein Generation | Apr 29, 2025 | Drug DiscoveryProtein Design | —Unverified | 0 |
| ProtTeX: Structure-In-Context Reasoning and Editing of Proteins with Large Language Models | Mar 11, 2025 | multimodal generationProtein Design | —Unverified | 0 |
| Recent advances in interpretable machine learning using structure-based protein representations | Sep 26, 2024 | Interpretable Machine LearningProtein Design | —Unverified | 0 |
| Reinforcement Learning for Sequence Design Leveraging Protein Language Models | Jul 3, 2024 | DiversityDrug Discovery | —Unverified | 0 |
| Rigidity strengthening is a vital mechanism for protein-ligand binding | Mar 31, 2017 | Drug DesignProtein Design | —Unverified | 0 |
| RNACG: A Universal RNA Sequence Conditional Generation model based on Flow-Matching | Jul 29, 2024 | Property PredictionProtein Design | —Unverified | 0 |
| Sparks: Multi-Agent Artificial Intelligence Model Discovers Protein Design Principles | Apr 26, 2025 | Protein Design | —Unverified | 0 |
| Steering Protein Family Design through Profile Bayesian Flow | Feb 11, 2025 | Protein Design | —Unverified | 0 |
| SurfPro: Functional Protein Design Based on Continuous Surface | May 7, 2024 | DecoderProtein Design | —Unverified | 0 |
| TERMinator: A Neural Framework for Structure-Based Protein Design using Tertiary Repeating Motifs | Apr 27, 2022 | Protein Design | —Unverified | 0 |
| The Dance of Atoms-De Novo Protein Design with Diffusion Model | Apr 23, 2025 | HallucinationProtein Design | —Unverified | 0 |
| Controllable Protein Design with Language Models | Jan 18, 2022 | Protein DesignText Generation | —Unverified | 0 |
| Towards deep learning sequence-structure co-generation for protein design | Oct 2, 2024 | Deep LearningProtein Design | —Unverified | 0 |
| Toward the Explainability of Protein Language Models for Sequence Design | Jun 24, 2025 | Explainable artificial intelligenceExplainable Artificial Intelligence (XAI) | —Unverified | 0 |
| Training Free Guided Flow Matching with Optimal Control | Oct 23, 2024 | Image ManipulationProtein Design | —Unverified | 0 |
| Fast uncovering of protein sequence diversity from structure | Jun 17, 2024 | DiversityProtein Design | —Unverified | 0 |
| UniIF: Unified Molecule Inverse Folding | May 29, 2024 | AllDrug Discovery | —Unverified | 0 |
| Using GANs for De Novo Protein Design Targeting Microglial IL-3Rα to Inhibit Alzheimer's Progression | Apr 5, 2024 | Protein Design | —Unverified | 0 |
| Validation of an LLM-based Multi-Agent Framework for Protein Engineering in Dry Lab and Wet Lab | Nov 9, 2024 | Protein DesignProtein Folding | —Unverified | 0 |
| Void distributions reveal structural link between jammed packings and protein cores | Oct 31, 2018 | Protein Design | —Unverified | 0 |
| Plug-and-Play Controllable Generation for Discrete Masked Models | Oct 3, 2024 | Image GenerationProtein Design | —Unverified | 0 |
| Prediction of amino acid side chain conformation using a deep neural network | Jul 26, 2017 | PredictionProtein Design | —Unverified | 0 |
| Pre-training of Graph Neural Network for Modeling Effects of Mutations on Protein-Protein Binding Affinity | Aug 28, 2020 | Drug DesignGraph Neural Network | —Unverified | 0 |
| Prot42: a Novel Family of Protein Language Models for Target-aware Protein Binder Generation | Apr 6, 2025 | DecoderProtein Design | —Unverified | 0 |
| ProtDAT: A Unified Framework for Protein Sequence Design from Any Protein Text Description | Dec 5, 2024 | DescriptiveProtein Design | —Unverified | 0 |
| ProteinBench: A Holistic Evaluation of Protein Foundation Models | Sep 10, 2024 | Protein Design | —Unverified | 0 |
| Protein design by multiobjective optimization: evolutionary and non-evolutionary approaches | Jul 1, 2017 | Combinatorial OptimizationEfficient Exploration | —Unverified | 0 |
| Protein Design with Dynamic Protein Vocabulary | May 25, 2025 | Protein DesignProtein Language Model | —Unverified | 0 |