SOTAVerified

Protein Design

Formally, given the design requirements of users, models are required to generate protein amino acid sequences that align with those requirements.

Papers

Showing 101150 of 175 papers

TitleStatusHype
Enhancing the efficiency of protein language models with minimal wet-lab data through few-shot learning0
Fast and Accurate Antibody Sequence Design via Structure Retrieval0
Fast fixed-backbone protein sequence and rotamer design0
Folding and Stabilization of Native-Sequence-Reversed Proteins0
From thermodynamics to protein design: Diffusion models for biomolecule generation towards autonomous protein engineering0
Annotation-guided Protein Design with Multi-Level Domain Alignment0
Generative AI for Controllable Protein Sequence Design: A Survey0
Generative artificial intelligence for de novo protein design0
Generative modeling for protein structures0
Geometric deep learning assists protein engineering. Opportunities and Challenges0
Gradient-Informed Quality Diversity for the Illumination of Discrete Spaces0
Ideal gas behavior of rotamerically defined conformers in native globular proteins0
Implicitly Guided Design with PropEn: Match your Data to Follow the Gradient0
Improving Protein Sequence Design through Designability Preference Optimization0
Iterative Importance Fine-tuning of Diffusion Models0
Lattice protein design using Bayesian learning0
Learning immune receptor representations with protein language models0
Leveraging Deep Generative Model For Computational Protein Design And Optimization0
CCPL: Cross-modal Contrastive Protein Learning0
ProteinWeaver: A Divide-and-Assembly Approach for Protein Backbone Design0
ProteinZero: Self-Improving Protein Generation via Online Reinforcement Learning0
ProtFlow: Fast Protein Sequence Design via Flow Matching on Compressed Protein Language Model Embeddings0
ProT-GFDM: A Generative Fractional Diffusion Model for Protein Generation0
ProtTeX: Structure-In-Context Reasoning and Editing of Proteins with Large Language Models0
Recent advances in interpretable machine learning using structure-based protein representations0
Reinforcement Learning for Sequence Design Leveraging Protein Language Models0
Rigidity strengthening is a vital mechanism for protein-ligand binding0
RNACG: A Universal RNA Sequence Conditional Generation model based on Flow-Matching0
Sparks: Multi-Agent Artificial Intelligence Model Discovers Protein Design Principles0
Steering Protein Family Design through Profile Bayesian Flow0
SurfPro: Functional Protein Design Based on Continuous Surface0
TERMinator: A Neural Framework for Structure-Based Protein Design using Tertiary Repeating Motifs0
The Dance of Atoms-De Novo Protein Design with Diffusion Model0
Controllable Protein Design with Language Models0
Towards deep learning sequence-structure co-generation for protein design0
Toward the Explainability of Protein Language Models for Sequence Design0
Training Free Guided Flow Matching with Optimal Control0
Fast uncovering of protein sequence diversity from structure0
UniIF: Unified Molecule Inverse Folding0
Using GANs for De Novo Protein Design Targeting Microglial IL-3Rα to Inhibit Alzheimer's Progression0
Validation of an LLM-based Multi-Agent Framework for Protein Engineering in Dry Lab and Wet Lab0
Void distributions reveal structural link between jammed packings and protein cores0
Plug-and-Play Controllable Generation for Discrete Masked Models0
Prediction of amino acid side chain conformation using a deep neural network0
Pre-training of Graph Neural Network for Modeling Effects of Mutations on Protein-Protein Binding Affinity0
Prot42: a Novel Family of Protein Language Models for Target-aware Protein Binder Generation0
ProtDAT: A Unified Framework for Protein Sequence Design from Any Protein Text Description0
ProteinBench: A Holistic Evaluation of Protein Foundation Models0
Protein design by multiobjective optimization: evolutionary and non-evolutionary approaches0
Protein Design with Dynamic Protein Vocabulary0
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Benchmark Results

#ModelMetricClaimedVerifiedStatus
1GraphTransPerplexity6.63Unverified
2StructGNNPerplexity6.4Unverified
3AlphaDesignPerplexity6.3Unverified
4GCAPerplexity6.05Unverified
5GVPPerplexity5.36Unverified
6ProteinMPNNPerplexity4.61Unverified
7PiFoldPerplexity4.55Unverified
8Knowledge-DesignPerplexity3.46Unverified
#ModelMetricClaimedVerifiedStatus
1ESM-IFPerplexity6.44Unverified
2GVP-largePerplexity6.17Unverified