SOTAVerified

Protein Design

Formally, given the design requirements of users, models are required to generate protein amino acid sequences that align with those requirements.

Papers

Showing 1120 of 175 papers

TitleStatusHype
Fine-Tuning Discrete Diffusion Models via Reward Optimization with Applications to DNA and Protein DesignCode2
RNAFlow: RNA Structure & Sequence Design via Inverse Folding-Based Flow MatchingCode2
Out of Many, One: Designing and Scaffolding Proteins at the Scale of the Structural Universe with Genie 2Code2
Fast protein backbone generation with SE(3) flow matchingCode2
Hypergraph Isomorphism ComputationCode2
Mol-Instructions: A Large-Scale Biomolecular Instruction Dataset for Large Language ModelsCode2
Knowledge-Design: Pushing the Limit of Protein Design via Knowledge RefinementCode2
DiffDock-PP: Rigid Protein-Protein Docking with Diffusion ModelsCode2
A Text-guided Protein Design FrameworkCode2
Geometry-Complete Diffusion for 3D Molecule Generation and OptimizationCode2
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Benchmark Results

#ModelMetricClaimedVerifiedStatus
1GraphTransPerplexity6.63Unverified
2StructGNNPerplexity6.4Unverified
3AlphaDesignPerplexity6.3Unverified
4GCAPerplexity6.05Unverified
5GVPPerplexity5.36Unverified
6ProteinMPNNPerplexity4.61Unverified
7PiFoldPerplexity4.55Unverified
8Knowledge-DesignPerplexity3.46Unverified
#ModelMetricClaimedVerifiedStatus
1ESM-IFPerplexity6.44Unverified
2GVP-largePerplexity6.17Unverified