SOTAVerified

Protein Design

Formally, given the design requirements of users, models are required to generate protein amino acid sequences that align with those requirements.

Papers

Showing 161170 of 175 papers

TitleStatusHype
Generative modeling for protein structures0
Void distributions reveal structural link between jammed packings and protein cores0
A natural upper bound to the accuracy of predicting protein stability changes upon mutations0
Modular decomposition of protein structure using community detection0
Computational Protein Design with Deep Learning Neural Networks0
mGPfusion: Predicting protein stability changes with Gaussian process kernel learning and data fusionCode0
Variational auto-encoding of protein sequencesCode0
Prediction of amino acid side chain conformation using a deep neural network0
Protein design by multiobjective optimization: evolutionary and non-evolutionary approaches0
Rigidity strengthening is a vital mechanism for protein-ligand binding0
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Benchmark Results

#ModelMetricClaimedVerifiedStatus
1GraphTransPerplexity6.63Unverified
2StructGNNPerplexity6.4Unverified
3AlphaDesignPerplexity6.3Unverified
4GCAPerplexity6.05Unverified
5GVPPerplexity5.36Unverified
6ProteinMPNNPerplexity4.61Unverified
7PiFoldPerplexity4.55Unverified
8Knowledge-DesignPerplexity3.46Unverified
#ModelMetricClaimedVerifiedStatus
1ESM-IFPerplexity6.44Unverified
2GVP-largePerplexity6.17Unverified