Site-Agnostic 3D Dose Distribution Prediction with Deep Learning Neural Networks
Maryam Mashayekhi, Itzel Ramirez Tapia, Anjali Balagopal, Xinran Zhong, Azar Sadeghnejad Barkousaraie, Rafe McBeth, Mu-Han Lin, Steve Jiang, Dan Nguyen
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Typically, the current dose prediction models are limited to small amounts of data and require re-training for a specific site, often leading to suboptimal performance. We propose a site-agnostic, 3D dose distribution prediction model using deep learning that can leverage data from any treatment site, thus increasing the total data available to train the model. Applying our proposed model to a new target treatment site requires only a brief fine-tuning of the model to the new data and involves no modifications to the model input channels or its parameters. Thus, it can be efficiently adapted to a different treatment site, even with a small training dataset.