SOTAVerified

Generative Modeling with Conditional Autoencoders: Building an Integrated Cell

2017-04-28Code Available0· sign in to hype

Gregory R. Johnson, Rory M. Donovan-Maiye, Mary M. Maleckar

Code Available — Be the first to reproduce this paper.

Reproduce

Code

Abstract

We present a conditional generative model to learn variation in cell and nuclear morphology and the location of subcellular structures from microscopy images. Our model generalizes to a wide range of subcellular localization and allows for a probabilistic interpretation of cell and nuclear morphology and structure localization from fluorescence images. We demonstrate the effectiveness of our approach by producing photo-realistic cell images using our generative model. The conditional nature of the model provides the ability to predict the localization of unobserved structures given cell and nuclear morphology.

Reproductions