Federated Learning with LoRA Optimized DeiT and Multiscale Patch Embedding for Secure Eye Disease Recognition
Md. Naimur Asif Borno, Md Sakib Hossain Shovon, MD Hanif Sikder, Iffat Firozy Rimi, Tahani Jaser Alahmadi, Mohammad Ali Moni
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Recent progress in image-based medical disease detection encounters challenges such as limited annotated data sets, inadequate spatial feature analysis, data security issues, and inefficient training frameworks. This study introduces a data-efficient image transformer (DeIT)-based approach that overcomes these challenges by utilizing multiscale patch embedding for better feature extraction and stratified weighted random sampling to address class imbalance. The model also incorporates a LoRA-enhanced transformer encoder, a distillation framework, and federated learning for decentralized training, improving both efficiency and data security. Consequently, it achieves state-of-the-art performance, with the highest AUC, F1 score, precision, minimal loss, and Top-5 accuracy. Additionally, Grad-CAM++ visualizations improve interpretability by highlighting critical pathological regions, enhancing the model's clinical relevance. These results highlight the potential of this approach to advance AI-powered medical imaging and disease detection.