Correlation Analysis of Chronic Obstructive Pulmonary Disease (COPD) and its Biomarkers Using the Word Embeddings

Abstract

It is very costly and time consuming to find new biomarkers for specific diseases in clinical laboratories. In this study, to find new biomarkers most closely related to Chronic Obstructive Pulmonary Disease (COPD), which is widely known as respiratory disease, biomarkers known to be associated with respiratory diseases and COPD itself were converted into word embedding. And their similarities were measured. We used Word2Vec, Canonical Correlation Analysis (CCA), and Global Vector (GloVe) for word embedding. In order to replace the clinical evaluation, the titles and abstracts of papers retrieved from Google Scholars were analyzed and quantified to estimate the performance of the word em-bedding models.

Tasks

Reproductions