Automated Prediction of Paravalvular Regurgitation before Transcatheter Aortic Valve Implantation
Michele Cannito, Riccardo Renzulli, Adson Duarte, Farzad Nikfam, Carlo Alberto Barbano, Enrico Chiesa, Francesco Bruno, Federico Giacobbe, Wojciech Wanha, Arturo Giordano, Marco Grangetto, Fabrizio D'Ascenzo
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Abstract
Severe aortic stenosis is a common and life-threatening condition in elderly patients, often treated with Transcatheter Aortic Valve Implantation (TAVI). Despite procedural advances, paravalvular aortic regurgitation (PVR) remains one of the most frequent post-TAVI complications, with a proven impact on long-term prognosis. In this work, we investigate the potential of deep learning to predict the occurrence of PVR from preoperative cardiac CT. To this end, a dataset of preoperative TAVI patients was collected, and 3D convolutional neural networks were trained on isotropic CT volumes. The results achieved suggest that volumetric deep learning can capture subtle anatomical features from pre-TAVI imaging, opening new perspectives for personalized risk assessment and procedural optimization. Source code is available at https://github.com/EIDOSLAB/tavi.