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Mind the Detail: Uncovering Clinically Relevant Image Details in Accelerated MRI with Semantically Diverse Reconstructions

2025-07-01Code Available0· sign in to hype

Jan Nikolas Morshuis, Christian Schlarmann, Thomas Küstner, Christian F. Baumgartner, Matthias Hein

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Abstract

In recent years, accelerated MRI reconstruction based on deep learning has led to significant improvements in image quality with impressive results for high acceleration factors. However, from a clinical perspective image quality is only secondary; much more important is that all clinically relevant information is preserved in the reconstruction from heavily undersampled data. In this paper, we show that existing techniques, even when considering resampling for diffusion-based reconstruction, can fail to reconstruct small and rare pathologies, thus leading to potentially wrong diagnosis decisions (false negatives). To uncover the potentially missing clinical information we propose ``Semantically Diverse Reconstructions'' ( ), a method which, given an original reconstruction, generates novel reconstructions with enhanced semantic variability while all of them are fully consistent with the measured data. To evaluate automatically we train an object detector on the fastMRI+ dataset. We show that significantly reduces the chance of false-negative diagnoses (higher recall) and improves mean average precision compared to the original reconstructions. The code is available on https://github.com/NikolasMorshuis/SDR

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